Terbinafine. 250 mg. 28 table

€42
Tax included

Myconafine "is a synthetic product. Antifungal Its effect is due to inhibition of enzymes that play a key role in the formation of important fungal substances. Depending on the concentration, the product can destroy fungal cell

Quantity

Table terbinafine. 250 mg. 28 table

 Table terbinafine. 250 mg, Myconafine "is a synthetic product. Antifungal Its effect is due to inhibition of enzymes that play a key role in the formation of important fungal substances. Depending on the concentration, the product can destroy fungal cell

WHAT Myconafine "AND WHAT IT IS USED

Myconafine "is a synthetic product. Antifungal Its effect is due to inhibition of enzymes that play a key role in the formation of important fungal substances. Depending on the concentration, the product can destroy the fungal cell.

 

Myconafine is used to treat:

 

 onychomycosis (nail fungal infection) of the hands and feet caused by dermatophytes;

  Tinea capitis (fungal infection of the scalp);

  Fungal infections of the skin caused by dermatophytes;

  Mycosis of smooth skin - tinea corporis (body), tinea cruris (a calf), tinea pedis (on foot);

 Skin infections caused by organisms of the genus Candida (eg Candida albicans).

 

Unlike local forms of product Myconafine "tablet is not effective against Pityriasis versicolor.

 

 WHAT YOU NEED TO KNOW BEFORE TREATMENT WITH Myconafine

 

Product is used in hypersensitivity to Myconafine. "

 

In this medicinal product, please note the following:

 

The product is used with caution in patients with chronic or active liver disease. Prior to treatment is necessary to evaluate existing liver disease. In these cases, hepatotoxicity may occur.

 

Patients should be advised to monitor unexplained symptoms of nausea, anorexia, pain in the right upper abdominal pain or jaundice, dark urine and fatigue. In patients with pre-existing renal disease (creatinine clearance <50 ml / min) administration has not preporachva.Lechenieto the product should be discontinued at the onset of progressive morbilliform obriv.Ryadko can meet and skin reactions like syndrome Stevens-Johnson and toxic epidermal necrolysis, which also require discontinuation of therapy.

 

During treatment with Myconafine "can be found in the eye lens changes and retina.

 

In patients with immune deficiency necessary blood counts, particularly when treatment continues for more than six weeks. Upon the occurrence of secondary neutropenia (neutrophil count <1000 kl./mm3) treatment product is discontinued and appoint appropriate treatment.

 

Application Myconafine "when taking food and drink

 

Taking the product is not affected by food and drink.

 

Pregnancy

 

Before taking any medicines, check with your doctor or pharmacist

 

Since the treatment of nail fungus (onychomycosis) may be delayed, treatment is not recommended during pregnancy.

 

Breastfeeding

 

Before taking any medicines, check with your doctor or farmatsevtSled product acceptance he found in breast milk. The ratio between the amount in milk and plasma is 7:1 and therefore not be used during breastfeeding.

 

Driving and operating machinery

 

Myconafine "does not affect the ability to drive and use machines. Taking other lekarstvaMolya, tell your doctor or pharmacist if you are taking or have recently taken any other medicines, even if they have not been prescribed by a doctor

  Effect of other medicinal products on terbinafine - separation of terbinafine may be accelerated by drugs that increase metabolism and can be inhibited by drugs that inhibit the metabolism of certain enzymes in the liver (P450 enzyme system). In these cases it may be necessary to adjust dozata.Tsimetidin reduces the release of terbinafine by 33%. Rifampicin enhances separation by 100%.

  Effect of terbinafine on other drugs - not affect the excretion of antipyrine and digoxin. Terbinafine may increase the effects of caffeine by 19%.

 

Terbinafine inhibits the metabolism of products mediated by CYP2D6 tricyclic antidepressants, beta-blockers, selective serotonin reuptake inhibitors, antiarrhythmics class 1C products and MAO inhibitors Type B. It increases the clearance of desipramine by 15%. Terbinafine may reduce the effect of cyclosporine by 15%.

 

HOW TO APPLY Myconafine

 

Always Myconafine as your doctor! On prescription! The product is administered orally.

 Adults - 250 mg once daily.

 

Children over 2 years depending on the weight

<20 kg - 62,5 mg once daily (half tablet of 125 mg); 

20 to 40 kg - 125 mg once daily;

> 40 kg - 250 mg once daily.

The duration of treatment depends on the cause and location of the infection:

  In onychomycosis treatment arms still 6 weeks to 3 "months and with onychomycosis of the feet - 3 to 6 months, while abnormal growth of the nail may be needed longer treatment;

  Tinea capitis - 4 weeks;

  Skin infection - tinea pedis (interdigitalna, plantar type "loafers") - 2 to 6 weeks; tinea corporis, cruris-2 to 4 weeks;

  For smooth skin infections by dermatophytes and Candida skin - 2-4 weeks.

 

Elderly

 

There is no evidence that these patients require different dosages or the side effects of it are different from those in younger patients. We take into account the possibility of altered renal and hepatic function in these patient

 

If you take too much of the drug:

 

When taking a higher dose than prescribed immediately seek help from a doctor! Data Myconafine ® overdose is limited. Up to 5 g (20 times the therapeutic dose) were administered without serious adverse reactions. Symptoms usually include nausea, vomiting, abdominal pain, confusion, rash, frequent urination, headaches.

 

Recommended elimination of the product with activated charcoal and symptomatic therapy.

 

If you forget to Myconafine:

 

If you forget to take the next dose, take the missed dose as soon as possible, but do not take both to the next.

 

 POSSIBLE SIDE EFFECTS

 

Like all medicines, Myconafine can cause adverse reactions reaktsiiNezhelanite are ranked by frequency according to the following classification:

 

very common> 1/10, common> 1/100 to <1/10;

 

uncommon> 1/1000 to <1/100;

 

Rare> 1/10000 to <1/1000;

 

very rare <1/10000.

 

Blood and lymphatic system

 

Very rare

 

Neutropenia, agranulocytosis, thrombocytopenia

 

Immune System

 

Very rare

 

Anaphylactoid reactions (including angioedema), skin and systemic lupus erythematosus

 

Nervous system and psychiatric disorders

 

Common

ncommon

 

Headache

 

Disorders of taste loss, which is reversible after cessation of treatment, disturbed food intake

 

Gastrointestinal Disorders

 

Very common

 

Gastrointestinal symptoms - stomach fullness, loss of appetite, dyspepsia, nausea, mild abdominal pain, diarrhea

 

Hepatobiliary disorders

 

Rare

Hepato-biliary dysfunction, rarely liver failure

Skin and underlying tissues

Very common

Very rare

Non-serious forms of skin reactions (rash, urticaria) Serious skin reactions - Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized pustular psoriasis exanthemous-like attacks and exacerbation of psoriasis, hair loss, without any causal connection

 

Musculoskeletal, connective tissue and bone disorders

 

Very common

 

Musculoskeletal effects - arthralgia, myalgia

 

General disorders

 

Very rare

 

Fatigue

 

If you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. 

 

 STORAGE CONDITIONS

 

No special storage conditions. Keep out of reach of children! Do not use after the expiry date stated on the package! _Srok Life: three (3) years

Active substance in one tablet: Terbinafine hydrochloride, eq. Terbinafine 125 mg of
 
Active substance in one tablet: Terbinafine hydrochloride, eq. Terbinafine 250 mg of
 
Excipients: microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, hydroxypropyl methylcellulose-, magnesium stearate.

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