Cusimolol 2.5mg. 5ml.


Cusimolol is an anti-glaucoma drug and belongs to the group of beta-blockers (a non-selective beta-blocker).


Cusimolol 2.5mg. 5ml.


CUSIMOLOL eye drops containing as a drug substance timolol (timolol) 0.25% as timolol maleate (timolol maleate). CUZIMOLOL eye drops also contain excipients: benzalkonium chloride 0.01% (as a preservative), sodium chloride, sodium phosphate, disodium phosphate and purified water.

Cusimolol is eye drops, solution and is supplied in two different concentrations of the solution - 0.25%. The medicine is packed in a cardboard box containing a 5 ml plastic vial with a screw cap.

Cuzimolol is an anti-glaucoma drug and belongs to the group of beta-blockers (a non-selective beta-blocker).

Cusinolol (timolol) eye drops reduce intraocular pressure whether or not it is accompanied by glaucoma. The hypotensive effect (decrease) starts approximately 20 minutes after the initial drop. The maximum effect is usually observed one or two hours after topical application.

Cuzimolol 0.25% and Cuzimolol 0.5% eye drops, solution maintains intraocular pressure for 24 hours.

Indications (What is used for KYSIMILOL eye drops 0.25%)

Eye drops of Cuzimolol are indicated for the treatment of a reduction of elevated intraocular pressure in various conditions such as ocular hypertension (ocular hypertension), chronic open-angle glaucoma (including lens-relieved patients) and some cases of secondary glaucoma .

Contraindications (When not to use KUZIMOLOL eye drops 0.25%)

CUZIMOLOL eye drops should not be used in case of hypersensitivity to timolol or any of the substances listed in the formulation.

Pregnancy and breastfeeding

The use of CUZIMOLOL eye drops during pregnancy and lactation requires consultation with a doctor. Only be used if the potential benefit justifies the probable risk.

Use in children

Timolol for ocular administration is not recommended for use in children because the efficacy and safety of the medicinal product in this patient group has not been established.

Special warnings and precautions

If it is decided to change your antiglaucoma, the medication used (on the recommended dose) will be continued on the first day. The next day, the antiglaucoma initially used is stopped altogether and the treatment is continued with timolol (KUIMAILOL eye drops). Changing the antiglaucoma medicine is only done by your doctor. When timolol is used in conjunction with other medicines, the treatment is done according to the same dosing regimen. In combination therapy, individualization is a necessity and your treating physician should discontinue the use of any or all of the medicines as soon as the intraocular pressure is kept at a satisfactory level. Approximately four weeks are needed to show the effect of timolol (CUMZIOLOL eye drops) to stabilize the intraocular pressure. After this period it is necessary to check its values again. Due to the 24-hour variations in intraocular pressure, it should be measured at different times of the day.

CUZIMOLOL eye drops 0.25% and 0.5% contain a preservative (benzalkonium chloride) which has the property of depositing on soft contact lenses and changing their color. If you wear soft contact lenses, do not use the drops until the lenses are in your eyes. Wait 15 minutes after the drop before putting the lenses back.


In some cases, local administration of timolol in the eye may lead to systemic (cell-associated) beta-blocker typical side effects. Therefore, eye drops of Kuzimolol should be used with caution when systemic beta-blockers are contraindicated, such as: bronchial asthma, sinus bradycardia (pulse retardation), cardiogenic block, labile diabetes, first-degree atrial block.

Heart failure should be adequately compensated before starting treatment. Patients with a history of severe heart disease should be periodically monitored by monitoring the pulse, blood pressure and signs of congestive heart failure. Please consult your treating physician!

In patients treated with beta-blockers for oral administration, it should be considered that they may have an additional effect on intraocular pressure.

Drug Interactions

Timolol can potentiate the effect of systemically administered beta-blockers (B / g Attention!). In some cases of epinephrine combination therapy, enlargement of the pupil has been reported. The use of timolol on its own does not lead to changes in the size of the pupil.

How to use CUZIMOLOL eye drops 0.25% and 0.5%?


You should use CUZIMOLOL eye drops as directed by your doctor. The drops should be placed twice a day (morning and evening) - this will keep the inside
Instructions for proper use:

• Dripping should be done under hygienic conditions. Always wash your hands before using eye drops.

• Tilt your head backwards. Dissolve the eyelid so that it forms a "pocket" between it and the eye. The drop should fall into that place, called the conjunctive sac.

• Do not touch the tip of the bottle applicator-dropper to any surface to protect the solution from dirt.

• After use, immediately insert the bottle cap and close it tightly.


Due to the fact that the medicinal product is intended for topical use, toxic effects are not expected when used at the recommended therapeutic dose. At higher doses, the medicinal product may cause nausea or heart discomfort. Depending on the amount, appropriate symptomatic treatment should be given. In case of overdosage or accidental ingestion, please consult your doctor immediately.

Adverse drug reactions

Cuzimolol (0.25% and 0.5%) eye drops, solution is usually well tolerated. Occasionally, inflammation and redness of the eyes (including short stones, blepharitis, keratitis), visual disturbances (including refractory changes that are most commonly caused by the cessation of previous mystic therapy). Very rarely, hypersensitivity, including localized and generalized urticaria or rash, may occur. However, very rarely, reactions associated with the systemic action of beta-blockers may occur, including moderate bradycardia (pulse delay ), hypotension (lowering of blood pressure), bronchospasm (predominantly in patients with a history of asthma), congestive heart failure and masked symptoms of hypoglycaemia in insulin-dependent diabetics. The following side effects have been observed rarely and their causal relationship to local timolol use has not been established, such as headache, dry mouth, anorexia (lack of appetite), dyspepsia (nausea), nausea, hypertension (high blood pressure), arrhythmia, anaphylactic macular edema (part of the eye), central nervous system reactions (fatigue, confusion, depression, anxiety, sleepiness).

Please, if you notice any side effects not mentioned in this leaflet, tell your doctor or pharmacist immediately!


• KUSIMOLOL eye drops 0.25% solution should be stored in a place protected from light at temperatures below 30 ° C.

• The pack should be discarded four weeks after the initial opening.

• Do not use after the expiry date stated on the carton - on the carton and label (EXP).

• Keep out of reach of children!

Medicinal products are registered in Bulgaria:

Cusimolol 0.25% eye drops



New product